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KMID : 0606320010170010095
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Journal of Phamacetical Sciences Sookmyung Women s University
2001 Volume.17 No. 1 p.95 ~ p.99
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Photolysisis and DNA Cleaving Activities of Haloacetphenone
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Jeon Ra-Ok
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Abstract
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The photolytic behaviors and DNA cleaving activities of the haloacetophenones; 4’-, and 2’-bromoacetophenones, 4’-chloroacetophenone, and bromofluoroacetophenones, which are phenyl radical precursors upon irradiation, have been investigated. Bromofluoroacetophenones revealed their potential as new photoinducible DNA cleaving agents comparing with 4’-bromoacetophenone.
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